A database of hormones and their receptors |
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HMRbase accession number | 10230 |
Swiss-prot Accession number | Q9YGV6 (Sequence in FASTA format) |
Description | Prolactin precursor (PRL). |
Source organism | Paralichthys olivaceus (Japanese flounder) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Pleuronectiformes;Pleuronectoidei; Paralichthyidae; Paralichthys. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the somatotropin/prolactin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 211 Amino acids |
Molecular weight | 23340 |
References | 1 Kim Y.T., Lee S.Y.; "Flounder prolactin."; Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.
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Domain Name | Hormone_1 |
Hormone Name | Prolactin |
Mature Hormone Sequence | VPINDLLDRASQRSDQLHSLSTTLSQELDSHFPPIGRVIMPRPSMCHTSALQTPNDKTQALQVSESELLSLARSLLQAWADPLSALSSSAFSLPHPAQSSIFNKVREMQEHSKNLGDGLDILSGKMGEAAQALSSLPFRGNDVGQDRISKLINFHFLLSCFRRDSHKIDSFLKVLRCRAANTQPEMC |
Position of mature hormone in Pre-Hormone protein | 187 Residues from position (25-211) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10758 |
Swiss-prot Accession number | P09537 (Sequence in FASTA format) |
Description | Somatotropin precursor (Growth hormone). |
Source organism | Paralichthys olivaceus (Japanese flounder) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Pleuronectiformes;Pleuronectoidei; Paralichthyidae; Paralichthys. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the somatotropin/prolactin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation |
Protein Length | 190 Amino acids |
Molecular weight | 21453 |
References | 1 PubMed abstract 2567501 2 PubMed abstract 2909523 3 PubMed abstract 8522198 4 PubMed abstract 3194207 |
Domain Name | Hormone_1 |
Hormone Name | Somatotropin |
Mature Hormone Sequence | QPITENQRLFSIAVGRVQYLHLVAKKLFSDFENSLQLEDQRLLNKIASKEFCHSDNFLSPIDKHETQGSSVQKLLSVSYRLIESWEFFSRFLVASFAVRTQVTSKLSELKMGLLKLIEANQDGAGGFSESSVLQLTPYGNSELFACFKKDMHKVETYLTVAKCRLFPEANCTL |
Position of mature hormone in Pre-Hormone protein | 173 Residues from position (18-190) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 11181 |
Swiss-prot Accession number | O57312 (Sequence in FASTA format) |
Description | Cholecystokinins precursor (CCK) [Contains: Cholecystokinin 8 (CCK8)]. |
Source organism | Paralichthys olivaceus (Japanese flounder) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Pleuronectiformes;Pleuronectoidei; Paralichthyidae; Paralichthys. |
Subcellular location | Secreted (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the gastrin/cholecystokinin family. |
Tissue Specificity | N/A |
Post translational modification | The precursor is cleaved by enzymes to produce a number of active cholecystokinins (By similarity). |
Function | This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear |
Protein Length | 135 Amino acids |
Molecular weight | 14773 |
References | 1 PubMed abstract 11042006 |
Domain Name | Gastrin |
Hormone Name | Cholecystokinin |
Mature Hormone Sequence | HPISSQHLDEGQRSISTPSEALLEADTHSLGEPHLRQSRSAPQLKSLPVAEEDGDSRANLSELLARLISSRKGSVRRNSTAYSKGLSPNHRIADRDYLGWMDFGRRSAEEYEYSS |
Position of mature hormone in Pre-Hormone protein | 115 Residues from position (21-135) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 11182 |
Swiss-prot Accession number | O57312 (Sequence in FASTA format) |
Description | Cholecystokinins precursor (CCK) [Contains: Cholecystokinin 8 (CCK8)]. |
Source organism | Paralichthys olivaceus (Japanese flounder) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Pleuronectiformes;Pleuronectoidei; Paralichthyidae; Paralichthys. |
Subcellular location | Secreted (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the gastrin/cholecystokinin family. |
Tissue Specificity | N/A |
Post translational modification | The precursor is cleaved by enzymes to produce a number of active cholecystokinins (By similarity). |
Function | This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear |
Protein Length | 135 Amino acids |
Molecular weight | 14773 |
References | 1 PubMed abstract 11042006 |
Domain Name | Gastrin |
Hormone Name | Cholecystokinin 8 |
Mature Hormone Sequence | DYLGWMDF |
Position of mature hormone in Pre-Hormone protein | 8 Residues from position (116-123) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |